Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | HTR1A | P08908 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.51 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.50 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.50 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12325717 | 0.80 | SIGMAR1 (0.76) | SIGMAR1ALDH1A1HTR1ATSHRRAB9A | |
| SCHEMBL12325748 | 0.80 | SIGMAR1 (0.76) | SIGMAR1KDM4EALDH1A1KMT2AHTR1A | |
| SCHEMBL7294373 | 0.78 | SIGMAR1 (0.60) | SIGMAR1KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL28298203 | 0.78 | CHRM2 (0.79) | KDM4EALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7295692 | 0.77 | SIGMAR1 (1.00) | SIGMAR1ALDH1A1MEN1KMT2AHTR1A | |
| SCHEMBL8946079 | 0.77 | SIGMAR1 (0.67) | SIGMAR1KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL12325670 | 0.77 | SIGMAR1 (0.75) | SIGMAR1KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL12325719 | 0.75 | SIGMAR1 (0.69) | SIGMAR1KDM4EALDH1A1HTR1ATSHR | |
| SCHEMBL18177883 | 0.74 | MEN1 (0.70) | SIGMAR1KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL7304070 | 0.74 | SIGMAR1 (0.70) | SIGMAR1KDM4EALDH1A1HTR1ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0580503-B1 | Aminoalkylchromones, process for their preparation and compositions containing them | ADIR (FR) | 1995-06-14 | — | — | EP | disclosed |
| EP-0580503-A1 | Aminoalkylchromones, process for their preparation and compositions containing them | ADIR ET COMPAGNIE (FR) | 1994-01-26 | — | — | EP | disclosed |