Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | HTR1A | P08908 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 3/20 | 0.49 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | TNF | P01375 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | DRD4 | P21917 | 2/20 | 0.41 |
| ▸ | DRD3 | P35462 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12325717 | 0.83 | SIGMAR1 (0.76) | SIGMAR1ALDH1A1RAB9AHTR1ATSHR | |
| SCHEMBL12325748 | 0.83 | SIGMAR1 (0.76) | SIGMAR1ALDH1A1RAB9AHTR1ATSHR | |
| SCHEMBL7295692 | 0.81 | SIGMAR1 (1.00) | SIGMAR1ALDH1A1RAB9AHTR1ATSHR | |
| SCHEMBL12325670 | 0.80 | SIGMAR1 (0.75) | SIGMAR1ALDH1A1RAB9AHTR1ATSHR | |
| SCHEMBL12325719 | 0.79 | SIGMAR1 (0.69) | SIGMAR1ALDH1A1RAB9AHTR1ATSHR | |
| SCHEMBL7304070 | 0.77 | SIGMAR1 (0.70) | SIGMAR1ALDH1A1RAB9AHTR1ATSHR | |
| SCHEMBL7307865 | 0.77 | SIGMAR1 (0.62) | SIGMAR1ALDH1A1RAB9AHTR1ATSHR | |
| SCHEMBL8946184 | 0.76 | SIGMAR1 (0.65) | SIGMAR1ALDH1A1RAB9AHTR1ACYP11B1 | |
| SCHEMBL7305251 | 0.74 | SIGMAR1 (0.76) | SIGMAR1ALDH1A1RAB9AHTR1ATSHR | |
| SCHEMBL7303032 | 0.73 | SIGMAR1 (0.70) | SIGMAR1ALDH1A1RAB9AHTR1ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5519023-A | SCHIZOPHRENIA | ADIR ET COMPAGNIE (FR) | 1996-05-21 | — | — | US | disclosed |