Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | GRM5 | P41594 | 1/20 | 0.56 |
| ▸ | HTR7 | P34969 | 1/20 | 0.54 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 2/20 | 0.49 |
| ▸ | DRD4 | P21917 | 2/20 | 0.49 |
| ▸ | DRD3 | P35462 | 2/20 | 0.49 |
| ▸ | RBP4 | P02753 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6979597 | 0.99 | SMN1; SMN2 (0.57) | SMN1; SMN2GRM5HTR7AKR1C3KMT2A | |
| SCHEMBL12781876 | 0.83 | TSHR (0.61) | SMN1; SMN2GRM5HTR7AKR1C3KMT2A | |
| Hydrochloric Acid SCHEMBL27486758 | 0.83 | ADRA2C (0.50) | SMN1; SMN2KMT2AMEN1MAPTTSHR | |
| SCHEMBL7838958 | 0.81 | GRM5 (0.62) | SMN1; SMN2GRM5HTR7AKR1C3KMT2A | |
| Hydrochloric Acid SCHEMBL6987606 | 0.79 | GRM5 (0.59) | SMN1; SMN2GRM5HTR7AKR1C3KMT2A | |
| SCHEMBL12431991 | 0.79 | HTR7 (0.54) | SMN1; SMN2GRM5HTR7AKR1C3KMT2A | |
| SCHEMBL9565829 | 0.78 | AKR1C3 (0.62) | SMN1; SMN2GRM5HTR7AKR1C3KMT2A | |
| Hydrochloric Acid SCHEMBL6976133 | 0.78 | HTR7 (0.62) | SMN1; SMN2GRM5HTR7AKR1C3KMT2A | |
| SCHEMBL11157921 | 0.78 | GRM5 (0.69) | GRM5HTR7AKR1C3KMT2AMEN1 | |
| SCHEMBL3999891 | 0.77 | HTR7 (0.58) | SMN1; SMN2GRM5HTR7AKR1C3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0771565-A2 | Angiogenesis inhibitor | Senju Pharmaceutical Co., Ltd. (JP) | 1997-05-07 | — | — | EP | disclosed |