Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.47 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3069331 | 0.89 | ALDH1A1 (0.55) | KMT2AMEN1ALDH1A1NPC1RAB9A | |
| SCHEMBL3862551 | 0.81 | MASP2 (0.46) | KMT2AMEN1LMNANPC1RAB9A | |
| Toluene SCHEMBL10507527 | 0.80 | SMN1; SMN2 (0.53) | KMT2AMEN1LMNAALDH1A1NPC1 | |
| SCHEMBL22890735 | 0.79 | MAPT (0.49) | KMT2AMEN1LMNAALDH1A1NPC1 | |
| SCHEMBL23918991 | 0.78 | LMNA (0.64) | KMT2AMEN1LMNAALDH1A1NPC1 | |
| SCHEMBL6876467 | 0.77 | LMNA (0.53) | KMT2AMEN1LMNAALDH1A1NPC1 | |
| SCHEMBL20118384 | 0.77 | SLC1A3 (0.44) | KMT2AMEN1LMNAALDH1A1NPC1 | |
| SCHEMBL6994749 | 0.77 | LMNA (0.57) | KMT2AMEN1LMNAALDH1A1NPC1 | |
| SCHEMBL21939284 | 0.76 | LMNA (0.52) | KMT2AMEN1LMNAALDH1A1NPC1 | |
| SCHEMBL14861320 | 0.76 | LMNA (0.52) | KMT2AMEN1LMNAALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6455529-B1 | OXAZOLIDIN-2-ONE DERIVATIVES; ANTICOAGULANTS; ANTIMETASTASIS, ANTICARCINOGENIC, ANTIISCHEMIC, AND ANTIINFLAMMATORY AGENTS; OSTEOPOROSIS, ARTERIOSCLEROSIS | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 2002-09-24 | — | — | US | disclosed |
| EP-0741133-A2 | Adhesion receptor antagonists | MERCK PATENT GmbH (DE) | 1996-11-06 | — | — | EP | disclosed |