SCHEMBL7308324

SCHEMBL7308324

CC(C)c1cc(OS(=O)(=O)N(C)C)cc2c1C(=O)N(C)S2(=O)=O

nearest known ligand 0.41

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ELANE P08246 20/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7004780 0.64 ELANE (0.66) ELANE
SCHEMBL7305972 0.63 ELANE (0.68) ELANE
SCHEMBL7238810 0.63 ELANE (0.65) ELANE
SCHEMBL7307278 0.63 ELANE (0.58) ELANE
SCHEMBL7381092 0.62 ELANE (0.60) ELANE
SCHEMBL7276065 0.60 ELANE (0.71) ELANE
SCHEMBL7312357 0.59 ELANE (0.70) ELANE
SCHEMBL9127871 0.59 ELANE (0.47) ELANE
SCHEMBL17058602 0.59 RAB9A (0.49)
SCHEMBL9129683 0.58 ELANE (0.44) ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0594257-B1 2-Saccharinylmethyl aryl carboxylates useful as proteolytic enzyme inhibitors and compositions and method of use thereof STERLING WINTHROP INC (US) 1996-07-10 EP disclosed