Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 20/20 | 0.44 |
| ▸ | CTSG | P08311 | 1/20 | 0.44 |
| ▸ | CEL | P19835 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9127871 | 0.90 | ELANE (0.47) | ELANECTSGCEL | |
| SCHEMBL7004780 | 0.61 | ELANE (0.66) | ELANE | |
| SCHEMBL7238810 | 0.60 | ELANE (0.65) | ELANE | |
| SCHEMBL7305972 | 0.60 | ELANE (0.68) | ELANE | |
| SCHEMBL7307278 | 0.60 | ELANE (0.58) | ELANE | |
| SCHEMBL7308324 | 0.58 | ELANE (0.41) | ELANE | |
| SCHEMBL7095969 | 0.57 | ELANE (0.51) | ELANE | |
| SCHEMBL8813362 | 0.55 | ELANE (0.51) | ELANE | |
| SCHEMBL7336223 | 0.55 | ELANE (0.54) | ELANE | |
| SCHEMBL19088240 | 0.55 | SYK (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5455255-A | Inhibitor of proteolytic enzymes, for treatment of emphysema, rheumatoid arthritis, pancreatitis | STERLING WINTHROP INC. (US) | 1995-10-03 | — | — | US | disclosed |