Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 19/20 | 0.46 |
| ▸ | ACE2 | Q9BYF1 | 6/20 | 0.46 |
| ▸ | REN | P00797 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7308435 | 1.00 | ACE (0.46) | ACEACE2RENLMNA | |
| SCHEMBL7307561 | 0.88 | ACE (0.38) | ACEACE2LMNA | |
| SCHEMBL7307829 | 0.84 | F2 (0.47) | ACEACE2 | |
| SCHEMBL7307838 | 0.84 | F2 (0.47) | ACEACE2 | |
| SCHEMBL7306032 | 0.83 | F2 (0.49) | — | |
| SCHEMBL7308390 | 0.83 | TACR1 (0.44) | ACE | |
| SCHEMBL7309067 | 0.83 | ACE (0.41) | ACEACE2 | |
| SCHEMBL7308379 | 0.83 | TACR1 (0.44) | ACE | |
| SCHEMBL7306042 | 0.83 | F2 (0.49) | — | |
| SCHEMBL7309074 | 0.83 | ACE (0.41) | ACEACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1041064-A2 | N-substituted alpha aminoacid amides as calcium channel modulators | ELI LILLY AND COMPANY LIMITED (GB) | 2000-10-04 | — | — | EP | disclosed |
| EP-0805147-A1 | Novel N-substituted alpha aminoacid amides as calcium channel modulators | LILLY INDUSTRIES LIMITED (GB) | 1997-11-05 | — | — | EP | disclosed |