Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 7/20 | 0.70 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.70 |
| ▸ | FPR2 | P25090 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.42 |
| ▸ | CCR1 | P32246 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7310770 | 0.95 | ITGB3 (0.78) | ITGB3ITGA2BFPR2KMT2AHCRTR2 | |
| SCHEMBL7315714 | 0.89 | ITGB3 (0.75) | ITGB3ITGA2BP2RY12CCR1 | |
| SCHEMBL7302533 | 0.82 | ITGB3 (0.54) | ITGB3ITGA2BKMT2ARAB9AP2RY12 | |
| SCHEMBL7282972 | 0.78 | ITGB3 (0.86) | ITGB3ITGA2BKMT2A | |
| SCHEMBL7310657 | 0.78 | ITGB3 (0.57) | ITGB3ITGA2BFPR2GAARAB9A | |
| SCHEMBL2007668 | 0.76 | ITGB3 (0.58) | ITGB3ITGA2B | |
| SCHEMBL7310059 | 0.75 | ITGB3 (0.64) | ITGB3ITGA2BFPR2P2RY12CCR1 | |
| SCHEMBL7294592 | 0.75 | ITGB3 (0.75) | ITGB3ITGA2B | |
| SCHEMBL8381348 | 0.75 | ITGB3 (0.75) | ITGB3ITGA2B | |
| SCHEMBL13744638 | 0.73 | ITGB3 (0.79) | ITGB3ITGA2BGAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0741133-A2 | Adhesion receptor antagonists | MERCK PATENT GmbH (DE) | 1996-11-06 | — | — | EP | disclosed |