Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 6/20 | 0.57 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.57 |
| ▸ | P2RY12 | Q9H244 | 5/20 | 0.41 |
| ▸ | FPR2 | P25090 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CCR1 | P32246 | 1/20 | 0.39 |
| ▸ | CYP51A1 | Q16850 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7310059 | 0.96 | ITGB3 (0.64) | ITGB3ITGA2BP2RY12FPR2CCR1 | |
| SCHEMBL7307129 | 0.90 | ITGB3 (0.60) | ITGB3ITGA2BP2RY12CCR1 | |
| SCHEMBL7317008 | 0.85 | ITGB3 (0.45) | ITGB3ITGA2BP2RY12GAA | |
| SCHEMBL7317003 | 0.85 | ITGB3 (0.43) | ITGB3ITGA2BP2RY12 | |
| SCHEMBL7307131 | 0.81 | ITGB3 (0.41) | ITGB3ITGA2BGAA | |
| SCHEMBL7308440 | 0.78 | ITGB3 (0.70) | ITGB3ITGA2BP2RY12FPR2GAA | |
| SCHEMBL7310664 | 0.78 | ITGB3 (0.38) | ITGB3ITGA2BGAA | |
| SCHEMBL7310063 | 0.77 | ITGB3 (0.40) | ITGB3ITGA2B | |
| SCHEMBL7310770 | 0.74 | ITGB3 (0.78) | ITGB3ITGA2BFPR2CCR1 | |
| SCHEMBL7317284 | 0.72 | CTSL (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0741133-A2 | Adhesion receptor antagonists | MERCK PATENT GmbH (DE) | 1996-11-06 | — | — | EP | disclosed |