Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 10/20 | 0.75 |
| ▸ | ITGA2B | P08514 | 10/20 | 0.75 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PREP | P48147 | 1/20 | 0.41 |
| ▸ | FAP | Q12884 | 1/20 | 0.41 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | CCR1 | P32246 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7308440 | 0.89 | ITGB3 (0.70) | ITGB3ITGA2BP2RY12CCR1 | |
| SCHEMBL7310770 | 0.86 | ITGB3 (0.78) | ITGB3ITGA2BCCR1 | |
| SCHEMBL7302533 | 0.85 | ITGB3 (0.54) | ITGB3ITGA2BKDM4EP2RY12CHRM2 | |
| Sibrafiban SCHEMBL27618015 | 0.81 | ITGB3 (1.00) | ITGB3ITGA2B | |
| Sibrafiban SCHEMBL50759 | 0.81 | ITGB3 (1.00) | ITGB3ITGA2B | |
| SCHEMBL13283231 | 0.78 | ITGB3 (0.67) | ITGB3ITGA2BPREPFAP | |
| SCHEMBL7307129 | 0.77 | ITGB3 (0.60) | ITGB3ITGA2BKDM4EP2RY12CHRM2 | |
| Ro-44-3888 SCHEMBL7284509 | 0.76 | ITGB3 (1.00) | ITGB3ITGA2B | |
| Ro-44-3888 SCHEMBL7283142 | 0.76 | ITGB3 (1.00) | ITGB3ITGA2B | |
| SCHEMBL8770179 | 0.75 | ITGB3 (0.74) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0741133-A2 | Adhesion receptor antagonists | MERCK PATENT GmbH (DE) | 1996-11-06 | — | — | EP | disclosed |