Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ACE | P12821 | 1/20 | 0.32 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.32 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.32 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7300118 | 0.83 | RAB9A (0.33) | — | |
| SCHEMBL12395175 | 0.80 | — | — | |
| SCHEMBL8141483 | 0.68 | — | — | |
| SCHEMBL11179340 | 0.67 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL3369579 | 0.66 | — | — | |
| SCHEMBL10948087 | 0.66 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL10948081 | 0.66 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL932564 | 0.65 | CSNK2A2 (0.48) | MEN1KMT2ACSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL43717 | 0.65 | CSNK2A2 (0.48) | MEN1KMT2ACSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL7906023 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0728746-A1 | Azepinone compounds useful in the inhibition of ACE and NEP | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-08-28 | — | — | EP | disclosed |