SCHEMBL7308652

SCHEMBL7308652

[O]c1cc(Br)c(Br)c(Br)c1

nearest known ligand 0.53

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
APEX1 P27695 1/20 0.53
CA2 P00918 2/20 0.36
CA4 P22748 2/20 0.36
CA1 P00915 1/20 0.36
CA6 P23280 1/20 0.36
TDP1 Q9NUW8 1/20 0.35
AKR1B1 P15121 1/20 0.31
EIF2AK2 P19525 1/20 0.30
CSNK2A2 P19784 1/20 0.30
CSNK2B P67870 1/20 0.30
CSNK2A1 P68400 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12816712 0.71 APEX1 (0.44) APEX1CA2CA4CA1CA6
SCHEMBL7170676 0.69 APEX1 (1.00) APEX1CA2CA4CA1CA6
SCHEMBL6660944 0.69 APEX1 (0.60) APEX1CA2CA4CA1CA6
SCHEMBL12817864 0.67 APEX1 (0.40) APEX1CA2CA4CA1CA6
SCHEMBL12817289 0.67 TDP1 (0.43) APEX1CA2CA4CA1CA6
SCHEMBL5004546 0.67 ALDH1A1 (0.36)
SCHEMBL1047316 0.67
Water SCHEMBL28122788 0.67 APEX1 (0.92) APEX1CA2CA4CA1CA6
SCHEMBL28013373 0.67 APEX1 (0.56) APEX1CA2CA4CA1CA6
SCHEMBL12816770 0.65 TDP1 (0.41) APEX1CA2CA4CA1CA6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10124326-B2 Modified solid polyalkylaluminoxane and catalyst for olefin oligomerization reaction SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-11-13 US disclosed
US-20170225155-A1 MODIFIED SOLID POLYALKYLALUMINOXANE AND CATALYST FOR OLEFIN OLIOGOMERIZATION REACTION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-08-10 US disclosed
EP-3202822-A1 MODIFIED SOLID POLYALKYLALUMINOXANE AND CATALYST FOR OLEFIN OLIGOMERIZATION REACTION Sumitomo Chemical Company Limited (JP) 2017-08-09 EP disclosed
WO-2012133921-A1 CATALYST FOR OLEFIN OLIGOMERIZATION AND METHOD FOR PRODUCING α-OLEFIN SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-10-04 WO disclosed
US-5639776-A CROP PESTICIDE; NONPHYTOTOXIC, KIDNEY BEANS, ORANGES OTSUKA KAGAKU KABUSHIKI KAISHA (JP) 1997-06-17 US disclosed
US-5629406-A AMINO ACID DERIVATIVES SANKYO COMPANY, LIMITED (JP) 1997-05-13 US disclosed
EP-0751130-A1 4,5-DIHYDROPYRAZOLE-5-THIONE DERIVATIVES AND ACARICIDE CONTAINING THE SAME OTSUKA KAGAKU KABUSHIKI KAISHA (JP) 1997-01-02 EP disclosed
EP-0587311-A1 Peptides capable of inhibiting the activity of HIV protease, their preparation and their therapeutic use SANKYO COMPANY LIMITED (JP) 1994-03-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170225155-A1 MODIFIED SOLID POLYALKYLALUMINOXANE AND CATALYST FOR OLEFIN OLIOGOMERIZATION REACTION OGFR, GFER, ITGB7 APEX1 1598/4885CA2 4544/4885CA4 3955/4885
US-10124326-B2 Modified solid polyalkylaluminoxane and catalyst for olefin oligomerization reaction GFER, OGFR, TECR APEX1 1328/4885CA2 4602/4885CA4 4204/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.