SCHEMBL6660944

SCHEMBL6660944

Brc1cc(Br)c(Br)c(Br)c1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APEX1 P27695 1/20 0.60
TDP1 Q9NUW8 3/20 0.53
CYP3A4 P08684 1/20 0.53
TSHR P16473 1/20 0.53
GABRA1 P14867 1/20 0.45
GABRB1 P18505 1/20 0.45
GABRA2 P47869 1/20 0.45
GABRB2 P47870 1/20 0.45
AHR P35869 2/20 0.41
CA2 P00918 2/20 0.40
CA4 P22748 2/20 0.40
CA1 P00915 1/20 0.40
CA6 P23280 1/20 0.40
ALOX15 P16050 5/20 0.39
ALOX12 P18054 3/20 0.39
AKR1B1 P15121 3/20 0.39
HSP90AA1 P07900 1/20 0.36
TLR9 Q9NR96 1/20 0.36
ALDH1A1 P00352 1/20 0.36
MAPK1 P28482 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11789281 0.82 GABRA1 (0.52) APEX1TDP1CYP3A4TSHRGABRA1
SCHEMBL7111466 0.77 TDP1 (0.41) APEX1TDP1CYP3A4TSHRGABRA1
SCHEMBL12610870 0.77 AKR1B1 (0.43) APEX1TDP1CYP3A4TSHRGABRA1
SCHEMBL591287 0.77 CYP3A4 (0.55) APEX1TDP1CYP3A4TSHRGABRA1
SCHEMBL12816770 0.77 TDP1 (0.41) APEX1TDP1CYP3A4TSHRGABRA1
SCHEMBL7111469 0.77 TDP1 (0.41) APEX1TDP1CYP3A4TSHRGABRA1
SCHEMBL4450031 0.77 TDP1 (0.41) APEX1TDP1CYP3A4TSHRGABRA1
SCHEMBL28667897 0.77 TDP1 (0.41) APEX1TDP1CYP3A4TSHRGABRA1
SCHEMBL7516654 0.76 ALDH1A1 (0.57) APEX1TDP1CYP3A4TSHRGABRA1
Benzenethiol SCHEMBL27872637 0.76 ALDH1A1 (0.39) APEX1TDP1CYP3A4TSHRGABRA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 368 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5110901-A Polythioethers PHILLIPS PETROLEUM COMPANY (US) 1992-05-05 US claimed
US-5077374-A Reacting sulfur and a diphenyl ether in a polyhaloaromatic sol vent using a Friedel-crafts catalyst to obtain a polyphenoxathiinylene sulfide; heat resistance; circuits; capacitors PHILLIPS PETROLEUM COMPANY (US) 1991-12-31 US claimed
US-12577376-B2 Molded articles with laser-formed pattern Celanese Interntaional Corporation (US) 2026-03-17 US disclosed
US-20260042903-A1 Laser Transmissive Polyarylene Sulfide Composition TICONA LLC (US) 2026-02-12 US disclosed
US-20260045417-A1 Film Capacitor Containing A Polyarylene Sulfide TICONA LLC (US) 2026-02-12 US disclosed
EP-4662727-A1 NONAQUEOUS ELECTROCHEMICAL BATTERY CONTAINING A SEALING MEMBER Ticona LLC (US) 2025-12-17 EP disclosed
EP-4626738-A1 PYROTECHNIC SWITCH FOR AN ELECTRIC VEHICLE Ticona LLC (US) 2025-10-08 EP disclosed
EP-4626953-A1 HYDROLYTICALLY STABLE POLYARYLENE SULFIDE COMPOSITION Ticona LLC (US) 2025-10-08 EP disclosed
US-20250289956-A1 Polymer Composition With Improved Thermal Shock Resistance TICONA LLC 2025-09-18 US disclosed
US-20250250422-A1 Polyarylene Sulfide Composition With Improved Crystallization Properties TICONA LLC 2025-08-07 US disclosed
EP-2836555-B1 DYNAMICALLY VULCANIZED POLYARYLENE SULFIDE COMPOSITION TICONA LLC (US) 2025-07-09 EP disclosed
US-4282347-A AGING, RESISTANT FIBERS PHILLIPS PETROLEUM COMPANY (US) 1981-08-04 US disclosed
US-4174359-A HALOGEN COMPOUND MOBAY CHEMICAL CORPORATION (US) 1979-11-13 US disclosed
EP-0001096-A2 Flame retardant polycarbonate blends Mobay Chemical Corporation (US) 1979-03-21 EP disclosed
US-4116947-A FROM P-DIHALOBENZENE, POLYHALO AROMATIC COMPOUND, ALKALI METAL SULFIDE, N-ALKYL LACTAM AND WATER PHILLIPS PETROLEUM COMPANY (US) 1978-09-26 US disclosed
US-4089847-A Temperature programming in the production of arylene sulfide polymers PHILLIPS PETROLEUM COMPANY (US) 1978-05-16 US disclosed
US-4064114-A Production of arylene sulfide polymers PHILLIPS PETROLEUM COMPANY (US) 1977-12-20 US disclosed
US-4038261-A DIHALOBENZENE AND ALKALI METAL SULFIDE REACTANTS, A POLYHALO AROMATIC COMPOUND WHICH REDUCES MELT FLOW PHILLIPS PETROLEUM COMPANY (US) 1977-07-26 US disclosed
US-4038262-A PRODUCTION OF ARYLENE SULFIDE POLYMERS PHILLIPS PETROLEUM COMPANY (US) 1977-07-26 US disclosed
US-4025496-A Sequenced addition of components in poly(arylene sulfide) production PHILLIPS PETROLEUM COMPANY (US) 1977-05-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260042903-A1 Laser Transmissive Polyarylene Sulfide Composition TRPC5, TRPC3, TRPC7 APEX1 1562/4885TDP1 3537/4885CYP3A4 1644/4885
US-12577376-B2 Molded articles with laser-formed pattern LAS1L, PIM2, YES1 APEX1 4811/4885TDP1 3201/4885CYP3A4 3456/4885
US-20260045417-A1 Film Capacitor Containing A Polyarylene Sulfide SLC39A3, SLC39A11, SLC39A14 APEX1 2472/4885TDP1 4674/4885CYP3A4 2412/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.