Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.55 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.55 |
| ▸ | LTA4H | P09960 | 3/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.31 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.31 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7310784 | 0.99 | ITGB3 (0.54) | ITGB3ITGA2BLTA4HHRH3ALDH1A1 | |
| SCHEMBL7314678 | 0.99 | ITGB3 (0.54) | ITGB3ITGA2BLTA4HHRH3ALDH1A1 | |
| SCHEMBL7310413 | 0.99 | ITGB3 (0.54) | ITGB3ITGA2BLTA4HHRH3ALDH1A1 | |
| SCHEMBL7312611 | 0.91 | ITGB3 (0.49) | ITGB3ITGA2BLTA4H | |
| SCHEMBL7286717 | 0.91 | ITGB3 (0.47) | ITGB3ITGA2BMAPT | |
| Lefradafiban SCHEMBL7080546 | 0.90 | ITGB3 (0.62) | ITGB3ITGA2BLTA4HHRH3IRAK4 | |
| Lefradafiban SCHEMBL50399 | 0.90 | ITGB3 (0.62) | ITGB3ITGA2BLTA4HHRH3IRAK4 | |
| SCHEMBL7314181 | 0.90 | ITGB3 (0.49) | ITGB3ITGA2BLTA4HHRH3 | |
| SCHEMBL7284983 | 0.87 | ITGB3 (0.58) | ITGB3ITGA2BHRH3ALDH1A1IRAK4 | |
| SCHEMBL7282312 | 0.87 | ITGB3 (0.58) | ITGB3ITGA2BLTA4HHRH3IRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567966-B1 | Cyclic imino derivatives, medicaments containing these compounds and processes for the production thereof | BOEHRINGER INGELHEIM PHARMA (DE) | 1998-09-02 | — | — | EP | disclosed |
| US-5576444-A | ANTICOAGULANTS | DR. KARL THOMAE GMBH (DE) | 1996-11-19 | — | — | US | disclosed |
| EP-0567966-A1 | Cyclic imino derivatives, medicaments containing these compounds and processes for the production thereof | Dr. Karl Thomae GmbH (DE) | 1993-11-03 | — | — | EP | disclosed |