Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRG2 | P18507 | 6/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 6/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 5/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.42 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7317516 | 0.83 | GABRA3 (0.48) | GABRG2GABRB3GABRA3TP53GABRA5 | |
| SCHEMBL7353479 | 0.83 | GABRA3 (0.57) | GABRG2GABRB3GABRA3TP53GABRA5 | |
| SCHEMBL7285884 | 0.81 | GABRA3 (0.47) | GABRG2GABRB3GABRA3TP53GABRA5 | |
| SCHEMBL7317652 | 0.80 | GABRA3 (0.60) | GABRG2GABRB3GABRA3GABRA5GABRA1 | |
| SCHEMBL11628537 | 0.80 | GABRG2 (0.66) | GABRG2GABRB3GABRA3GABRA5GABRA1 | |
| SCHEMBL7306369 | 0.75 | GABRA1 (0.49) | GABRG2GABRB3GABRA3TP53GABRA5 | |
| SCHEMBL7350434 | 0.75 | GABRA1 (0.49) | GABRG2GABRB3GABRA3TP53GABRA5 | |
| SCHEMBL11017220 | 0.74 | GABRG2 (0.50) | GABRG2GABRB3GABRA3GABRA5GABRA1 | |
| SCHEMBL7318749 | 0.74 | GABRG2 (0.53) | GABRG2GABRB3GABRA3TP53GABRA5 | |
| SCHEMBL7317016 | 0.73 | GABRA1 (0.50) | GABRG2GABRB3GABRA3GABRA5GABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0109921-B1 | BENZODIAZEPINE RECEPTORS AND THEIR PREPARATION | A/S FERROSAN (DK) | 1988-03-02 | — | — | EP | disclosed |
| US-4507313-A | Oxadiazolyl-imidazo-[1,4]benzodiazepines and their use in treatment of diseases of the central nervous system | A/S FERROSAN (DK) | 1985-03-26 | — | — | US | disclosed |
| EP-0109921-A1 | Benzodiazepine receptors and their preparation | A/S FERROSAN (DK) | 1984-05-30 | — | — | EP | disclosed |