Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 6/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 4/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5617596 | 0.88 | MAOB (0.67) | MAOBKDM4EMAPTACHEMAOA | |
| SCHEMBL7314399 | 0.82 | MAOB (0.55) | MAOBKDM4EACHEMAOA | |
| SCHEMBL7311265 | 0.82 | ALDH1A1 (0.42) | MAOBKDM4EMAPT | |
| SCHEMBL7304194 | 0.81 | MAOB (0.78) | MAOBKDM4EMAPTACHE | |
| SCHEMBL9136381 | 0.77 | MAOB (0.44) | MAOBKDM4EMAPT | |
| SCHEMBL7312144 | 0.73 | MAOB (0.47) | MAOBACHEMAOA | |
| SCHEMBL7302123 | 0.73 | MAOB (0.77) | MAOBACHEMAOA | |
| SCHEMBL7302999 | 0.72 | MAOB (0.49) | MAOBKDM4EACHEMAOA | |
| SCHEMBL7304856 | 0.72 | MAOB (0.48) | MAOBKDM4EMAPT | |
| SCHEMBL9311594 | 0.70 | ALDH1A1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5414006-A | Monoamine oxidase inhibitors | BASF AKTIENGESELLSCHAFT (DE) | 1995-05-09 | — | — | US | disclosed |
| EP-0594036-A1 | Arylalkyloxythiocoumarines, process for their preparation and therapeutical agents containing them | BASF Aktiengesellschaft (DE) | 1994-04-27 | — | — | EP | disclosed |