Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 6/20 | 0.55 |
| ▸ | ACHE | P22303 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7304194 | 0.83 | MAOB (0.78) | MAOBACHEALDH1A1KDM4EHPGD | |
| SCHEMBL7308829 | 0.82 | MAOB (0.53) | MAOBACHEKDM4EMAOA | |
| SCHEMBL7317654 | 0.77 | ACHE (0.42) | MAOBACHEALDH1A1KDM4EHPGD | |
| SCHEMBL7302123 | 0.75 | MAOB (0.77) | MAOBACHEMAOA | |
| SCHEMBL7312144 | 0.75 | MAOB (0.47) | MAOBACHEMAOA | |
| SCHEMBL9139305 | 0.75 | MAOB (0.47) | MAOBALDH1A1KDM4ECYP1A2CYP2C9 | |
| SCHEMBL7302999 | 0.74 | MAOB (0.49) | MAOBACHEALDH1A1KDM4EHPGD | |
| SCHEMBL7301156 | 0.73 | MAOB (0.70) | MAOBACHEALDH1A1KDM4EHPGD | |
| SCHEMBL7304856 | 0.72 | MAOB (0.48) | MAOBALDH1A1KDM4EHPGDSMN1; SMN2 | |
| Atibeprone SCHEMBL2111018 | 0.71 | MAOB (1.00) | MAOBACHEMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5414006-A | Monoamine oxidase inhibitors | BASF AKTIENGESELLSCHAFT (DE) | 1995-05-09 | — | — | US | disclosed |
| EP-0594036-A1 | Arylalkyloxythiocoumarines, process for their preparation and therapeutical agents containing them | BASF Aktiengesellschaft (DE) | 1994-04-27 | — | — | EP | disclosed |