Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CHRNB2 | P17787 | 6/20 | 0.37 |
| ▸ | CHRNA2 | Q15822 | 6/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 4/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15482936 | 0.81 | EGLN2 (0.40) | HSD17B10KDM4EALDH1A1HTTL3MBTL1 | |
| SCHEMBL15482942 | 0.80 | HTT (0.36) | KDM4EALDH1A1HTTL3MBTL1CHRNB2 | |
| SCHEMBL7219002 | 0.79 | ALDH1A1 (0.38) | TSHRHSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL25248651 | 0.77 | HPGDS (0.38) | HSD17B10KDM4EALDH1A1HPGDHTT | |
| SCHEMBL30399972 | 0.77 | GABRP (0.41) | TSHRHSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL15483101 | 0.76 | HTT (0.38) | KDM4EALDH1A1HTTL3MBTL1CHRNB2 | |
| SCHEMBL29395265 | 0.75 | CYP11B1 (0.37) | KDM4EALDH1A1HTTL3MBTL1PTGER4 | |
| SCHEMBL25239312 | 0.75 | CYP11B1 (0.37) | KDM4EALDH1A1HTTL3MBTL1PTGER4 | |
| SCHEMBL31326191 | 0.73 | S100A9 (0.36) | KDM4EALDH1A1HTTL3MBTL1PTGER4 | |
| SCHEMBL21503685 | 0.73 | HSD17B10 (0.49) | TSHRHSD17B10KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0200024-A2 | 3-Cyano-pyridines, process for their preparation and their pharmaceutical use | ARZNEIMITTELWERK DRESDEN GmbH (DE) | 1986-11-05 | — | — | EP | disclosed |