Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | SLC9A1 | P19634 | 7/20 | 0.61 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14027284 | 0.97 | ALDH1A1 (0.63) | ALDH1A1SLC9A1EGLN3MAPTNPC1 | |
| SCHEMBL11120445 | 0.83 | ALDH1A1 (0.68) | ALDH1A1SLC9A1EGLN3MAPTNPC1 | |
| SCHEMBL14796568 | 0.81 | SLC9A1 (0.79) | SLC9A1EGLN3MAPTNPC1RAB9A | |
| SCHEMBL7672503 | 0.80 | SLC9A1 (0.71) | SLC9A1EGLN3MAPTNPC1RAB9A | |
| SCHEMBL22058723 | 0.78 | GRM2 (0.65) | ALDH1A1SLC9A1HSD17B10KDM4ETDP1 | |
| SCHEMBL7667065 | 0.78 | SLC9A1 (0.70) | SLC9A1EGLN3MAPTNPC1RAB9A | |
| SCHEMBL6790333 | 0.77 | TDP1 (0.71) | MAPTRAB9ATDP1L3MBTL1 | |
| SCHEMBL17103011 | 0.76 | SLC9A1 (0.90) | SLC9A1EGLN3MAPTNPC1RAB9A | |
| SCHEMBL6850915 | 0.76 | SLC9A1 (0.71) | SLC9A1EGLN3MAPTNPC1RAB9A | |
| SCHEMBL15076276 | 0.76 | SLC9A1 (0.71) | SLC9A1EGLN3MAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5081131-A | Omega-((hetero)alkyl)benz(cd)-indol-2-amines | AMERICAN CYANAMID COMPANY (US) | 1992-01-14 | — | — | US | disclosed |
| EP-0230035-A2 | Omega-[(hetero)alkyl]benz[cd]indol-2-amines | AMERICAN CYANAMID COMPANY (US) | 1987-07-29 | — | — | EP | disclosed |