Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | THRA | P10827 | 1/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7317467 | 0.86 | NPC1 (0.43) | NPC1RAB9AKMT2ATHRBALDH1A1 | |
| SCHEMBL7309403 | 0.81 | KMT2A (0.47) | NPC1RAB9AKMT2ATHRBALDH1A1 | |
| SCHEMBL7319372 | 0.71 | ALDH1A1 (0.47) | NPC1RAB9AKMT2ATHRBALDH1A1 | |
| SCHEMBL7317460 | 0.70 | KMT2A (0.46) | NPC1RAB9AKMT2ATHRBALDH1A1 | |
| SCHEMBL7311180 | 0.69 | PDE3B (0.47) | NPC1RAB9AKMT2AALDH1A1LMNA | |
| SCHEMBL19457041 | 0.69 | NPC1 (0.70) | NPC1RAB9AKMT2AALDH1A1MEN1 | |
| SCHEMBL4072151 | 0.68 | NPC1 (0.85) | NPC1RAB9AKMT2AALDH1A1MEN1 | |
| SCHEMBL7306695 | 0.68 | PDE3B (0.47) | NPC1RAB9AKMT2ATHRBALDH1A1 | |
| SCHEMBL7316869 | 0.68 | MAOB (0.49) | NPC1RAB9AKMT2A | |
| SCHEMBL7314782 | 0.67 | KMT2A (0.47) | NPC1RAB9AKMT2ATHRBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |