Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7309403 | 0.85 | KMT2A (0.47) | KMT2AMEN1NPC1RAB9AALDH1A1 | |
| SCHEMBL7310331 | 0.84 | PKM (0.43) | KMT2AMEN1NPC1RAB9AALDH1A1 | |
| SCHEMBL7314782 | 0.84 | KMT2A (0.47) | KMT2AMEN1NPC1RAB9AALDH1A1 | |
| SCHEMBL7317467 | 0.83 | NPC1 (0.43) | KMT2AMEN1NPC1RAB9AALDH1A1 | |
| SCHEMBL7319695 | 0.81 | ALDH1A1 (0.46) | KMT2ANPC1RAB9AALDH1A1MAPK1 | |
| SCHEMBL7306695 | 0.80 | PDE3B (0.47) | KMT2AMEN1NPC1RAB9AALDH1A1 | |
| SCHEMBL7316869 | 0.78 | MAOB (0.49) | KMT2ANPC1RAB9ASMN1; SMN2PDE3B | |
| SCHEMBL10374643 | 0.77 | NPC1 (0.43) | KMT2AMEN1NPC1RAB9AALDH1A1 | |
| SCHEMBL7318596 | 0.77 | NPC1 (0.43) | KMT2AMEN1NPC1RAB9AALDH1A1 | |
| SCHEMBL10374758 | 0.76 | NPC1 (0.44) | KMT2AMEN1NPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |