Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ERN1 | O75460 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7310264 | 0.95 | TSHR (0.37) | ALDH1A1HTTERN1KDM4EKMT2A | |
| SCHEMBL7318982 | 0.91 | TSHR (0.43) | ALDH1A1HTTERN1KDM4EKMT2A | |
| Hydrochloric Acid SCHEMBL7309503 | 0.89 | TSHR (0.42) | ALDH1A1HTTERN1KDM4EKMT2A | |
| SCHEMBL7315249 | 0.86 | TNF (0.39) | ALDH1A1HTTKDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL7309407 | 0.85 | TSHR (0.48) | ALDH1A1HTTERN1KDM4EKMT2A | |
| Hydrochloric Acid SCHEMBL7310273 | 0.84 | TSHR (0.47) | ALDH1A1HTTERN1KDM4EKMT2A | |
| SCHEMBL7311993 | 0.81 | SMN1; SMN2 (0.41) | ALDH1A1HTTKDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL7305457 | 0.81 | MCL1 (0.36) | ALDH1A1HTTKDM4EKMT2AMAPT | |
| SCHEMBL7318019 | 0.81 | ERN1 (0.33) | ALDH1A1ERN1KMT2ASMN1; SMN2TSHR | |
| SCHEMBL7310824 | 0.81 | ALDH1A1 (0.44) | ALDH1A1HTTERN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |