Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.39 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.38 |
| ▸ | ERN1 | O75460 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7309503 | 0.99 | TSHR (0.42) | TSHRCYSLTR2CYSLTR1ALDH1A1HTT | |
| SCHEMBL7309407 | 0.95 | TSHR (0.48) | TSHRALDH1A1HTTKDM4EERN1 | |
| Hydrochloric Acid SCHEMBL7310273 | 0.94 | TSHR (0.47) | TSHRALDH1A1HTTKDM4EERN1 | |
| SCHEMBL7309501 | 0.91 | ALDH1A1 (0.35) | TSHRALDH1A1HTTKDM4EERN1 | |
| SCHEMBL7315249 | 0.89 | TNF (0.39) | TSHRALDH1A1HTTKDM4EKMT2A | |
| SCHEMBL7310264 | 0.85 | TSHR (0.37) | TSHRALDH1A1HTTKDM4EERN1 | |
| SCHEMBL7315898 | 0.84 | ALDH1A1 (0.41) | ALDH1A1HTTKDM4EKMT2AMAPT | |
| SCHEMBL7311993 | 0.83 | SMN1; SMN2 (0.41) | TSHRALDH1A1HTTKDM4EKMT2A | |
| SCHEMBL7311758 | 0.82 | CNR2 (0.42) | TSHRALDH1A1HTTKDM4EKMT2A | |
| SCHEMBL7311187 | 0.82 | MCL1 (0.43) | TSHRPPARALTB4RMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |