Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ERN1 | O75460 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7309501 | 0.95 | ALDH1A1 (0.35) | TSHRERN1ALDH1A1MAPTKDM4E | |
| SCHEMBL7309407 | 0.90 | TSHR (0.48) | TSHRERN1ALDH1A1MAPTKDM4E | |
| Hydrochloric Acid SCHEMBL7310273 | 0.89 | TSHR (0.47) | TSHRERN1ALDH1A1MAPTKDM4E | |
| SCHEMBL7311993 | 0.86 | SMN1; SMN2 (0.41) | TSHRALDH1A1MAPTKDM4EKMT2A | |
| SCHEMBL7318982 | 0.85 | TSHR (0.43) | TSHRERN1ALDH1A1MAPTKDM4E | |
| Hydrochloric Acid SCHEMBL7309503 | 0.84 | TSHR (0.42) | TSHRERN1ALDH1A1MAPTKDM4E | |
| SCHEMBL7315249 | 0.81 | TNF (0.39) | TSHRALDH1A1MAPTKDM4EKMT2A | |
| SCHEMBL7315220 | 0.81 | S1PR4 (0.42) | ALDH1A1MAPTKDM4EGAAKMT2A | |
| SCHEMBL7317330 | 0.80 | ALDH1A1 (0.46) | ERN1ALDH1A1MAPTKDM4EKMT2A | |
| SCHEMBL7317861 | 0.79 | PDE3B (0.45) | TSHRALDH1A1KDM4EKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |