Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 14/20 | 0.48 |
| ▸ | CTSK | P43235 | 11/20 | 0.48 |
| ▸ | CTSS | P25774 | 10/20 | 0.48 |
| ▸ | CTSB | P07858 | 6/20 | 0.44 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7309429 | 0.86 | CTSL (0.45) | CTSLCTSKCTSSCTSBCACNA1B | |
| SCHEMBL7316501 | 0.85 | CTSL (0.44) | CTSLCTSKCTSSCTSBCACNA1B | |
| SCHEMBL7311694 | 0.80 | CTSL (0.44) | CTSLCTSKCTSSCTSBCACNA1B | |
| SCHEMBL7313591 | 0.79 | CCR1 (0.39) | — | |
| SCHEMBL7306148 | 0.73 | CTSL (0.51) | CTSLCTSKCTSSCTSB | |
| SCHEMBL7307986 | 0.73 | FNTA (0.42) | CTSKCTSS | |
| SCHEMBL7314922 | 0.73 | EBP (0.43) | — | |
| SCHEMBL7304422 | 0.73 | CTSL (0.50) | CTSLCTSKCTSSCTSB | |
| SCHEMBL7306594 | 0.72 | EBP (0.43) | — | |
| SCHEMBL7305541 | 0.72 | EBP (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1041064-A2 | N-substituted alpha aminoacid amides as calcium channel modulators | ELI LILLY AND COMPANY LIMITED (GB) | 2000-10-04 | — | — | EP | disclosed |
| EP-0805147-A1 | Novel N-substituted alpha aminoacid amides as calcium channel modulators | LILLY INDUSTRIES LIMITED (GB) | 1997-11-05 | — | — | EP | disclosed |