Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 8/20 | 0.44 |
| ▸ | CTSK | P43235 | 6/20 | 0.44 |
| ▸ | CTSS | P25774 | 5/20 | 0.44 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.44 |
| ▸ | CNR1 | P21554 | 4/20 | 0.41 |
| ▸ | CNR2 | P34972 | 4/20 | 0.41 |
| ▸ | EBP | Q15125 | 2/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | CTSB | P07858 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7316501 | 0.94 | CTSL (0.44) | CTSLCTSKCTSSCACNA1BEBP | |
| SCHEMBL7316023 | 0.88 | FNTA (0.43) | CTSKCTSSCNR1CNR2EBP | |
| SCHEMBL7304422 | 0.87 | CTSL (0.50) | CTSLCTSKCTSSEBPSIGMAR1 | |
| SCHEMBL7307986 | 0.83 | FNTA (0.42) | CTSKCTSSCNR1CNR2EBP | |
| SCHEMBL7314922 | 0.82 | EBP (0.43) | CNR1CNR2EBPSIGMAR1 | |
| SCHEMBL7309429 | 0.81 | CTSL (0.45) | CTSLCTSKCTSSCACNA1BCNR1 | |
| SCHEMBL7316936 | 0.81 | CTSL (0.49) | CTSLCTSKCTSSCACNA1BCTSB | |
| SCHEMBL7305541 | 0.81 | EBP (0.43) | CNR1CNR2EBPSIGMAR1 | |
| SCHEMBL7306594 | 0.81 | EBP (0.43) | CNR1CNR2EBPSIGMAR1 | |
| SCHEMBL7309730 | 0.80 | CTSL (0.48) | CTSLCTSKCTSSCACNA1BCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1041064-A2 | N-substituted alpha aminoacid amides as calcium channel modulators | ELI LILLY AND COMPANY LIMITED (GB) | 2000-10-04 | — | — | EP | disclosed |
| EP-0805147-A1 | Novel N-substituted alpha aminoacid amides as calcium channel modulators | LILLY INDUSTRIES LIMITED (GB) | 1997-11-05 | — | — | EP | disclosed |