Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EBP | Q15125 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
| ▸ | CCR1 | P32246 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7309094 | 0.88 | CNR1 (0.46) | EBPSIGMAR1CNR1CNR2CASP1 | |
| SCHEMBL30167338 | 0.88 | CNR1 (0.46) | EBPSIGMAR1CNR1CNR2CASP1 | |
| SCHEMBL7320577 | 0.86 | EBP (0.42) | EBPSIGMAR1CNR1CNR2CASP1 | |
| SCHEMBL7313305 | 0.85 | EBP (0.42) | EBPSIGMAR1CNR1CNR2CASP1 | |
| SCHEMBL11092926 | 0.84 | EBP (0.43) | EBPSIGMAR1CNR1CNR2EPHX2 | |
| SCHEMBL10423077 | 0.81 | CASP1 (0.60) | EBPSIGMAR1CNR1CNR2CASP1 | |
| SCHEMBL7322417 | 0.80 | CHRM2 (0.46) | EBPSIGMAR1EPHX2MEN1KMT2A | |
| Anipamil SCHEMBL247837 | 0.80 | SIGMAR1 (0.69) | EBPSIGMAR1EPHX2TSHRSCN5A | |
| Anipamil SCHEMBL31479919 | 0.80 | SIGMAR1 (0.69) | EBPSIGMAR1EPHX2TSHRSCN5A | |
| Anipamil SCHEMBL7199272 | 0.79 | SIGMAR1 (0.67) | EBPSIGMAR1EPHX2TSHRSCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4438131-A | CARDIOVASCULAR DISORDERS | BASF AKTIENGESELLSCHAFT (DE) | 1984-03-20 | — | — | US | disclosed |
| EP-0064158-A1 | Omega-cyano-1, omega-diphenyl azalcane derivatives, their preparation and pharmaceutical preparations containing them | BASF Aktiengesellschaft (DE) | 1982-11-10 | — | — | EP | disclosed |