Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR142 | Q7Z601 | 1/20 | 0.38 |
| ▸ | EED | O75530 | 1/20 | 0.37 |
| ▸ | MME | P08473 | 5/20 | 0.37 |
| ▸ | ACE | P12821 | 5/20 | 0.37 |
| ▸ | CPA1 | P15085 | 4/20 | 0.37 |
| ▸ | ACE2 | Q9BYF1 | 4/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.37 |
| ▸ | CTSS | P25774 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 1/20 | 0.37 |
| ▸ | PPID | Q08752 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7319612 | 0.92 | MME (0.38) | GPR142EEDMMEACECPA1 | |
| SCHEMBL7321193 | 0.92 | MME (0.43) | MMEACECPA1ACE2L3MBTL1 | |
| SCHEMBL7311112 | 0.91 | L3MBTL1 (0.40) | EEDL3MBTL1KLKB1NOD2 | |
| SCHEMBL7316899 | 0.90 | CYP3A4 (0.42) | L3MBTL1CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL7312621 | 0.87 | MMEL1 (0.48) | L3MBTL1 | |
| SCHEMBL7311908 | 0.87 | MMEL1 (0.48) | L3MBTL1 | |
| SCHEMBL7318799 | 0.85 | L3MBTL1 (0.41) | EEDMMEACECPA1ACE2 | |
| SCHEMBL7307856 | 0.85 | HRH4 (0.42) | L3MBTL1 | |
| SCHEMBL7340179 | 0.84 | L3MBTL1 (0.40) | MMEACECPA1ACE2L3MBTL1 | |
| SCHEMBL7317726 | 0.84 | L3MBTL1 (0.40) | L3MBTL1CYP3A4CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0511940-A2 | Phosphono/biaryl substituted dipeptide derivatives | CIBA-GEIGY AG (CH) | 1992-11-04 | — | — | EP | claimed |
| EP-0592367-A2 | Phosphono/biaryl substituted dipeptide derivatives | CIBA-GEIGY AG (CH) | 1994-04-13 | — | — | EP | disclosed |
| US-5294632-A | Diuretics and vasorelaxants | CIBA-GEIGY CORPORATION (US) | 1994-03-15 | — | — | US | disclosed |
| EP-0511940-A2 | Phosphono/biaryl substituted dipeptide derivatives | CIBA-GEIGY AG (CH) | 1992-11-04 | — | — | EP | disclosed |
| US-5155100-A | Treating cardiovascular disorders in mammals | CIBA-GEIGY CORPORATION (US) | 1992-10-13 | — | — | US | disclosed |