Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MMEL1 | Q495T6 | 2/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | REN | P00797 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7311112 | 0.95 | L3MBTL1 (0.40) | L3MBTL1MMEL1 | |
| SCHEMBL7310277 | 0.93 | CYP3A4 (0.42) | CYP3A4CYP2D6CYP2C19L3MBTL1MMEL1 | |
| SCHEMBL7317726 | 0.91 | L3MBTL1 (0.40) | CYP3A4CYP2D6CYP2C19L3MBTL1MMEL1 | |
| SCHEMBL7309787 | 0.90 | GPR142 (0.38) | CYP3A4CYP2D6CYP2C19L3MBTL1 | |
| SCHEMBL7321253 | 0.90 | L3MBTL1 (0.39) | CYP3A4CYP2D6CYP2C19L3MBTL1MMEL1 | |
| SCHEMBL7318799 | 0.89 | L3MBTL1 (0.41) | L3MBTL1MMEL1 | |
| SCHEMBL7311908 | 0.89 | MMEL1 (0.48) | L3MBTL1MMEL1 | |
| SCHEMBL7312621 | 0.89 | MMEL1 (0.48) | L3MBTL1MMEL1 | |
| SCHEMBL7307856 | 0.89 | HRH4 (0.42) | L3MBTL1MMEL1ALDH1A1 | |
| SCHEMBL7320312 | 0.88 | L3MBTL1 (0.39) | L3MBTL1MMEL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0592367-A2 | Phosphono/biaryl substituted dipeptide derivatives | CIBA-GEIGY AG (CH) | 1994-04-13 | — | — | EP | disclosed |
| US-5294632-A | Diuretics and vasorelaxants | CIBA-GEIGY CORPORATION (US) | 1994-03-15 | — | — | US | disclosed |
| EP-0511940-A2 | Phosphono/biaryl substituted dipeptide derivatives | CIBA-GEIGY AG (CH) | 1992-11-04 | — | — | EP | disclosed |
| US-5155100-A | Treating cardiovascular disorders in mammals | CIBA-GEIGY CORPORATION (US) | 1992-10-13 | — | — | US | disclosed |