Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
| ▸ | ANPEP | P15144 | 1/20 | 0.44 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.44 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 2/20 | 0.42 |
| ▸ | MMP9 | P14780 | 2/20 | 0.42 |
| ▸ | ACE | P12821 | 2/20 | 0.39 |
| ▸ | MME | P08473 | 1/20 | 0.39 |
| ▸ | MIF | P14174 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CPA1 | P15085 | 2/20 | 0.38 |
| ▸ | CPB1 | P15086 | 1/20 | 0.38 |
| ▸ | CPA3 | P15088 | 1/20 | 0.38 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.38 |
| ▸ | MMP7 | P09237 | 1/20 | 0.37 |
| ▸ | MMP12 | P39900 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7320285 | 0.86 | LTA4H (0.52) | LTA4HANPEPRNPEPDNPEPMMP2 | |
| SCHEMBL7320822 | 0.81 | LTA4H (0.47) | LTA4HANPEPRNPEPDNPEPMMP2 | |
| SCHEMBL7321248 | 0.81 | LTA4H (0.47) | LTA4HANPEPRNPEPDNPEPMMP2 | |
| SCHEMBL7321089 | 0.80 | LTA4H (0.40) | LTA4HMMP2MMP9MIFCYP1A2 | |
| SCHEMBL7318920 | 0.78 | CPA1 (0.62) | MMEMIFCYP1A2CPA1CPB1 | |
| SCHEMBL7313736 | 0.77 | LTA4H (0.43) | LTA4HANPEPRNPEPDNPEPCYP1A2 | |
| SCHEMBL7321257 | 0.77 | LTA4H (0.43) | LTA4HANPEPRNPEPDNPEPCYP1A2 | |
| SCHEMBL7317373 | 0.76 | MME (0.65) | LTA4HMMP2MMP9MMEMMP7 | |
| SCHEMBL7317368 | 0.76 | MME (0.65) | LTA4HMMP2MMP9MMEMMP7 | |
| SCHEMBL7310444 | 0.76 | LTA4H (0.42) | LTA4HANPEPRNPEPDNPEPMMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5459131-A | Renin inhibitors | AMERICAN CYANAMID COMPANY (US) | 1995-10-17 | — | — | US | disclosed |