Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7321257 | 1.00 | LTA4H (0.43) | LTA4HPPARGPPARAUSP2CYP3A4 | |
| SCHEMBL7320285 | 0.87 | LTA4H (0.52) | LTA4HCYP1A2KMOANPEPRNPEP | |
| SCHEMBL7310444 | 0.84 | LTA4H (0.42) | LTA4HKMOALDH1A1ANPEPRNPEP | |
| SCHEMBL7321600 | 0.81 | KMO (0.59) | PPARGPPARACYP1A2KMO | |
| SCHEMBL7320822 | 0.80 | LTA4H (0.47) | LTA4HCYP2C9KMOANPEPRNPEP | |
| SCHEMBL7323337 | 0.78 | MAPK1 (0.49) | ALDH1A1MEN1KMT2A | |
| SCHEMBL7309902 | 0.77 | LTA4H (0.48) | LTA4HCYP1A2ANPEPRNPEPDNPEP | |
| SCHEMBL7321248 | 0.76 | LTA4H (0.47) | LTA4HALDH1A1ANPEPRNPEPDNPEP | |
| SCHEMBL7321252 | 0.76 | BIRC2 (0.62) | USP2CYP3A4OPRM1NR1I2ADRB1 | |
| SCHEMBL7313729 | 0.76 | BIRC2 (0.62) | USP2CYP3A4OPRM1NR1I2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5459131-A | Renin inhibitors | AMERICAN CYANAMID COMPANY (US) | 1995-10-17 | — | — | US | disclosed |