Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | MIF | P14174 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | CPA1 | P15085 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CPB1 | P15086 | 1/20 | 0.33 |
| ▸ | CPA3 | P15088 | 1/20 | 0.33 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | FFAR2 | O15552 | 2/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9554635 | 0.83 | LTA4H (0.42) | LTA4HCPA1CPB1CPA3CPB2 | |
| SCHEMBL7309902 | 0.80 | LTA4H (0.48) | LTA4HMIFCPA1HPGDCPB1 | |
| SCHEMBL7310400 | 0.80 | MME (0.46) | LTA4HALDH1A1TSHR | |
| SCHEMBL7312789 | 0.80 | MME (0.46) | LTA4HALDH1A1TSHR | |
| SCHEMBL7312761 | 0.80 | MME (0.46) | LTA4HALDH1A1TSHR | |
| SCHEMBL7310410 | 0.80 | MME (0.46) | LTA4HALDH1A1TSHR | |
| SCHEMBL7321074 | 0.77 | BIRC2 (0.47) | ALDH1A1HSD17B10TSHR | |
| SCHEMBL9554926 | 0.75 | LTA4H (0.37) | LTA4HMAPTPOLBALDH1A1MEN1 | |
| SCHEMBL8524822 | 0.73 | NLN (0.39) | TDP1CPA1MMP2MMP9 | |
| SCHEMBL8524821 | 0.73 | NLN (0.39) | TDP1CPA1MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5459131-A | Renin inhibitors | AMERICAN CYANAMID COMPANY (US) | 1995-10-17 | — | — | US | disclosed |