Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | ACR | P10323 | 3/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | LDHA | P00338 | 2/20 | 0.36 |
| ▸ | LDHB | P07195 | 2/20 | 0.36 |
| ▸ | RORC | P51449 | 3/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | KLK1 | P06870 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.35 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7309972 | 0.89 | MAPT (0.47) | KMT2AACRPRSS1MEN1SMN1; SMN2 | |
| SCHEMBL1399030 | 0.88 | PRSS1 (0.42) | KMT2AACRPRSS1MEN1SMN1; SMN2 | |
| SCHEMBL1645315 | 0.86 | MAPT (0.51) | KMT2AACRPRSS1MEN1SMN1; SMN2 | |
| SCHEMBL9236106 | 0.83 | ACR (0.42) | KMT2AACRPRSS1MEN1SMN1; SMN2 | |
| SCHEMBL9231748 | 0.80 | ACR (0.40) | KMT2AACRPRSS1MEN1SMN1; SMN2 | |
| SCHEMBL9235998 | 0.80 | ACR (0.40) | KMT2AACRPRSS1MEN1SMN1; SMN2 | |
| SCHEMBL7307769 | 0.80 | ACR (0.45) | KMT2AACRPRSS1MEN1SMN1; SMN2 | |
| SCHEMBL11305091 | 0.79 | PRSS1 (0.42) | KMT2AACRPRSS1MEN1SMN1; SMN2 | |
| SCHEMBL11305070 | 0.78 | PRSS1 (0.53) | KMT2AACRPRSS1MEN1SMN1; SMN2 | |
| SCHEMBL1648216 | 0.77 | KMT2A (0.47) | KMT2AACRPRSS1MEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4021472-A | ANTIPLASMIN AND ANTITRYPSIN | ONO PHARMACEUTICAL CO., LTD. (JA) | 1977-05-03 | — | — | US | disclosed |