Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | BCKDK | O14874 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 4/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | PMM2 | O15305 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | MPI | P34949 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PHOSPHO1 | Q8TCT1 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
| ▸ | FBP1 | P09467 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1608964 | 0.72 | COMT (0.46) | MCL1MAPK1BCKDKRXFP1ALDH1A1 | |
| SCHEMBL9086480 | 0.71 | GPR35 (0.51) | GPR35HPGDALDH1A1PKMTDP1 | |
| SCHEMBL11521290 | 0.69 | TSHR (0.55) | MAPK1GPR35HPGDALDH1A1TDP1 | |
| SCHEMBL28410825 | 0.68 | CA1 (0.47) | MAPK1GPR35MAPTALDH1A1KDM4E | |
| SCHEMBL31057367 | 0.68 | CA1 (0.47) | MAPK1GPR35MAPTALDH1A1KDM4E | |
| SCHEMBL1608929 | 0.68 | CDK2 (0.44) | MCL1MAPK1BCKDKRXFP1GPR35 | |
| SCHEMBL4159524 | 0.67 | CASP6 (0.42) | GPR35TDP1CASP6 | |
| SCHEMBL18050231 | 0.67 | MCL1 (0.71) | MCL1MAPK1BCKDKRXFP1GPR35 | |
| Hydrochloric Acid SCHEMBL10855356 | 0.66 | MCL1 (0.69) | MCL1MAPK1BCKDKRXFP1BCL2L1 | |
| SCHEMBL5035719 | 0.66 | MCL1 (0.48) | MCL1MAPK1GPR35MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207701-B1 | AS ANTI-ANGIOGENIC, ANTI-ARTHRITIC, ANTI-INFLAMMATORY, ANTI-RETINOPATHIC, CONTRACEPTIVE AND TUMORISTATIC AGENTS | ABBOTT LABORATORIES | 2001-03-27 | — | — | US | disclosed |