Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.63 |
| ▸ | HTR2C | P28335 | 2/20 | 0.55 |
| ▸ | HTR7 | P34969 | 2/20 | 0.55 |
| ▸ | HTR6 | P50406 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9377572 | 0.99 | HTR2A (0.62) | HTR2AKDM4ECYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9375449 | 0.86 | HTR2A (0.56) | HTR2AKDM4ECYP1A2CYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL9374560 | 0.85 | HTR2A (0.55) | HTR2AKDM4ECYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7298960 | 0.83 | WNT3A (0.50) | HTR2AKDM4ECYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9672004 | 0.81 | HTR2A (0.66) | HTR2AKDM4ECYP1A2CYP3A4CYP2D6 | |
| SCHEMBL5760363 | 0.80 | HTR2A (0.61) | HTR2AKDM4ECYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11932544 | 0.79 | HTR2A (0.64) | HTR2AKDM4ECYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11758953 | 0.79 | KCNH2 (0.66) | HTR2AKDM4ECYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11370701 | 0.78 | HTR2A (0.61) | HTR2AKDM4ECYP1A2CYP3A4CYP2D6 | |
| SCHEMBL4211202 | 0.78 | HTR2A (1.00) | HTR2AKDM4ECYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0294183-B1 | Use of ethylamine derivatives as antihypertensive agents | AJINOMOTO KK (JP) | 1994-03-30 | — | — | EP | claimed |
| EP-0294183-A1 | Use of ethylamine derivatives as antihypertensive agents | AJINOMOTO CO., INC. (JP) | 1988-12-07 | — | — | EP | claimed |
| US-5229400-A | Cardiovascular disorders | AJINOMOTO CO., INC. (JP) | 1993-07-20 | — | — | US | disclosed |
| EP-0479601-A2 | Piperidine derivatives and their use as antiarrhythmic agents | Ajinomoto Co., Inc. (JP) | 1992-04-08 | — | — | EP | disclosed |