Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CCR1 | P32246 | 1/20 | 0.52 |
| ▸ | HTR2C | P28335 | 1/20 | 0.51 |
| ▸ | HTR7 | P34969 | 1/20 | 0.51 |
| ▸ | HTR6 | P50406 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9374560 | 0.99 | HTR2A (0.55) | HTR2AKDM4ECYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7310084 | 0.86 | HTR2A (0.63) | HTR2AKDM4ECYP1A2CYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL9377572 | 0.85 | HTR2A (0.62) | HTR2AKDM4ECYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11932544 | 0.79 | HTR2A (0.64) | HTR2AKDM4ECYP1A2CYP3A4CYP2D6 | |
| SCHEMBL7298960 | 0.77 | WNT3A (0.50) | HTR2AKDM4ECYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9672004 | 0.77 | HTR2A (0.66) | HTR2AKDM4ECYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11370701 | 0.77 | HTR2A (0.61) | HTR2AKDM4ECYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9374818 | 0.76 | HTR2A (0.50) | HTR2AKDM4ECYP1A2CYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL9375618 | 0.75 | HTR2A (0.49) | HTR2AKDM4ECYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11939045 | 0.75 | HTR2A (0.69) | HTR2AKDM4ECYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0294183-B1 | Use of ethylamine derivatives as antihypertensive agents | AJINOMOTO KK (JP) | 1994-03-30 | — | — | EP | claimed |