Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP6 | P55212 | 1/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 6/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 6/20 | 0.34 |
| ▸ | PDE2A | O00408 | 5/20 | 0.34 |
| ▸ | P2RY12 | Q9H244 | 5/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 2/20 | 0.32 |
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7320492 | 0.89 | CASP6 (0.36) | CASP6PDE3BPDE3APDE2AP2RY12 | |
| SCHEMBL7319354 | 0.87 | CASP6 (0.37) | CASP6PDE3BPDE3APDE2AP2RY12 | |
| SCHEMBL7310470 | 0.84 | KMT2A (0.37) | CASP6PDE3BPDE3APDE2AP2RY12 | |
| SCHEMBL7318852 | 0.84 | CASP6 (0.36) | CASP6PDE3BPDE3APDE2AP2RY12 | |
| SCHEMBL7313814 | 0.82 | CASP6 (0.36) | CASP6PDE3BPDE3APDE2AP2RY12 | |
| SCHEMBL7313559 | 0.81 | PDE3B (0.37) | CASP6PDE3BPDE3APDE2AP2RY12 | |
| SCHEMBL7314783 | 0.81 | CASP6 (0.35) | CASP6PDE3BPDE3APDE2AP2RY12 | |
| SCHEMBL7312110 | 0.79 | KMT2A (0.37) | CASP6PDE3BPDE3APDE2AP2RY12 | |
| SCHEMBL7316696 | 0.79 | CASP6 (0.35) | CASP6PDE3BPDE3APDE2AP2RY12 | |
| SCHEMBL7310679 | 0.79 | PDE3B (0.38) | CASP6PDE3BPDE3APDE2AP2RY12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |