Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP6 | P55212 | 1/20 | 0.36 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 4/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 4/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | HPD | P32754 | 3/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 2/20 | 0.33 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7313814 | 0.89 | CASP6 (0.36) | CASP6L3MBTL1MAPTPDE3BPDE3A | |
| SCHEMBL7312011 | 0.89 | CASP6 (0.38) | CASP6LTB4R2L3MBTL1LMNAMAPT | |
| SCHEMBL10376782 | 0.88 | PDE3B (0.40) | CASP6LTB4R2L3MBTL1MAPTPDE3B | |
| SCHEMBL7314783 | 0.87 | CASP6 (0.35) | CASP6L3MBTL1LMNAMAPTPDE3B | |
| SCHEMBL7310380 | 0.84 | CASP6 (0.36) | CASP6L3MBTL1MAPTPDE3BPDE3A | |
| SCHEMBL7311765 | 0.83 | CASP6 (0.35) | CASP6L3MBTL1MAPTPDE3BPDE3A | |
| SCHEMBL7320492 | 0.82 | CASP6 (0.36) | CASP6L3MBTL1MAPTPDE3BPDE3A | |
| SCHEMBL7303043 | 0.82 | CASP6 (0.35) | CASP6L3MBTL1PDE3BPDE3APDE2A | |
| SCHEMBL7317266 | 0.82 | PDE3B (0.48) | PDE3BPDE3ASMN1; SMN2PDE2AP2RY12 | |
| SCHEMBL7319354 | 0.81 | CASP6 (0.37) | CASP6L3MBTL1LMNAMAPTPDE3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |