Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 7/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 7/20 | 0.37 |
| ▸ | CASP6 | P55212 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | P2RY12 | Q9H244 | 3/20 | 0.34 |
| ▸ | PDE2A | O00408 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7316696 | 0.93 | CASP6 (0.35) | PDE3BPDE3ACASP6ALDH1A1KMT2A | |
| SCHEMBL7320425 | 0.89 | PDE3B (0.37) | PDE3BPDE3ACASP6ALDH1A1KMT2A | |
| SCHEMBL7312890 | 0.87 | CASP6 (0.37) | PDE3BPDE3ACASP6ALDH1A1KMT2A | |
| SCHEMBL7310470 | 0.83 | KMT2A (0.37) | PDE3BPDE3ACASP6ALDH1A1KMT2A | |
| SCHEMBL7311657 | 0.82 | L3MBTL1 (0.39) | PDE3BPDE3ACASP6ALDH1A1KMT2A | |
| SCHEMBL7319280 | 0.82 | CASP6 (0.35) | PDE3BPDE3ACASP6ALDH1A1KMT2A | |
| SCHEMBL7310380 | 0.81 | CASP6 (0.36) | PDE3BPDE3ACASP6ALDH1A1KMT2A | |
| SCHEMBL7308848 | 0.81 | PDE3B (0.44) | PDE3BPDE3AALDH1A1KMT2AP2RY12 | |
| SCHEMBL7321041 | 0.80 | CASP6 (0.35) | PDE3BPDE3ACASP6ALDH1A1KMT2A | |
| SCHEMBL7319397 | 0.80 | CASP6 (0.38) | PDE3BPDE3ACASP6ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |