Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 1/20 | 0.72 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.61 |
| ▸ | DRD3 | P35462 | 1/20 | 0.58 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7311113 | 0.87 | KCNA3 (0.71) | KCNA3SIGMAR1OPRM1 | |
| SCHEMBL7313939 | 0.84 | KCNA3 (1.00) | KCNA3OPRM1 | |
| SCHEMBL7309532 | 0.83 | KCNA3 (0.67) | KCNA3SIGMAR1OPRM1 | |
| SCHEMBL9052179 | 0.82 | DRD2 (0.67) | DRD3 | |
| SCHEMBL8437630 | 0.82 | OPRM1 (0.69) | DRD3OPRM1 | |
| SCHEMBL466815 | 0.81 | KCNA3 (0.64) | KCNA3SIGMAR1 | |
| SCHEMBL10274482 | 0.81 | OPRM1 (0.67) | DRD3OPRM1 | |
| Droxypropine SCHEMBL2110922 | 0.80 | DRD3 (0.53) | KCNA3DRD3OPRM1 | |
| SCHEMBL3554958 | 0.78 | KCNA3 (0.60) | KCNA3SIGMAR1OPRM1 | |
| SCHEMBL9052507 | 0.78 | DRD2 (0.71) | SIGMAR1DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5364867-A | For treatment of psychosis | STERLING WINTHROP INC. (US) | 1994-11-15 | — | — | US | claimed |
| US-5364867-A | For treatment of psychosis | STERLING WINTHROP INC. (US) | 1994-11-15 | — | — | US | disclosed |