Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 1/20 | 0.67 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.63 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7311113 | 0.88 | KCNA3 (0.71) | KCNA3SIGMAR1OPRM1 | |
| SCHEMBL7310478 | 0.83 | KCNA3 (0.72) | KCNA3SIGMAR1OPRM1 | |
| SCHEMBL466815 | 0.82 | KCNA3 (0.64) | KCNA3SIGMAR1 | |
| SCHEMBL7313939 | 0.80 | KCNA3 (1.00) | KCNA3OPRM1OPRD1OPRK1 | |
| SCHEMBL3554958 | 0.79 | KCNA3 (0.60) | KCNA3SIGMAR1OPRM1OPRD1OPRK1 | |
| SCHEMBL8096481 | 0.77 | SIGMAR1 (1.00) | KCNA3SIGMAR1OPRM1DRD2 | |
| SCHEMBL27873229 | 0.77 | OPRM1 (0.60) | OPRM1OPRD1OPRK1 | |
| SCHEMBL10924212 | 0.75 | SLC6A12 (0.53) | SIGMAR1DRD2 | |
| SCHEMBL9378157 | 0.75 | DRD2 (0.54) | OPRM1DRD2OPRD1OPRK1 | |
| SCHEMBL15961276 | 0.73 | SIGMAR1 (0.91) | SIGMAR1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5364867-A | For treatment of psychosis | STERLING WINTHROP INC. (US) | 1994-11-15 | — | — | US | claimed |
| US-5364867-A | For treatment of psychosis | STERLING WINTHROP INC. (US) | 1994-11-15 | — | — | US | disclosed |