Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 12/20 | 0.53 |
| ▸ | ADRB1 | P08588 | 11/20 | 0.53 |
| ▸ | ADRB3 | P13945 | 9/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7314684 | 0.85 | ADRB2 (0.56) | ADRB2ADRB1ADRB3MEN1KMT2A | |
| Fumaric Acid SCHEMBL7310602 | 0.85 | ADRB2 (0.56) | ADRB2ADRB1ADRB3MEN1KMT2A | |
| Fumaric Acid SCHEMBL7310590 | 0.85 | ADRB2 (0.56) | ADRB2ADRB1ADRB3MEN1KMT2A | |
| SCHEMBL7309393 | 0.81 | ADRB2 (0.54) | ADRB2ADRB1ADRB3MEN1KMT2A | |
| SCHEMBL10841198 | 0.73 | ADRB2 (0.56) | ADRB2ADRB1ADRB3MEN1KMT2A | |
| SCHEMBL7315388 | 0.73 | ADRB2 (0.58) | ADRB2ADRB1ADRB3MEN1KMT2A | |
| SCHEMBL7309404 | 0.72 | ADRB2 (0.57) | ADRB2ADRB1ADRB3MEN1KMT2A | |
| SCHEMBL7306021 | 0.72 | ADRB2 (0.54) | ADRB2ADRB1ADRB3MEN1KMT2A | |
| SCHEMBL7313756 | 0.72 | KMT2A (0.68) | ADRB2ADRB1KMT2ASLC6A4SLC6A3 | |
| SCHEMBL7307959 | 0.71 | ADRB2 (0.56) | ADRB2ADRB1ADRB3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4258062-A | ISOPRENALINE ANTAGONISTS EFFECTING HEART RATE AND BLOOD PRESSURE | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1981-03-24 | — | — | US | disclosed |
| US-4171370-A | Phenoxy-amino-propanols | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1979-10-16 | — | — | US | disclosed |