Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.49 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.46 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 13/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1015935 | 0.79 | ESR2 (0.58) | PRMT5WDR77GPR119KDM4E | |
| SCHEMBL7320226 | 0.79 | GPR119 (0.48) | GPR119KDM4EPKM | |
| SCHEMBL27007016 | 0.78 | HPGD (0.48) | GPR119KDM4EPKM | |
| SCHEMBL3005376 | 0.78 | ESR2 (0.52) | PRMT5WDR77GPR119KDM4E | |
| SCHEMBL4508565 | 0.77 | GPR119 (0.48) | GPR119KDM4EPKM | |
| SCHEMBL6152184 | 0.74 | HPGD (0.56) | GPR119KDM4EPKM | |
| SCHEMBL3159388 | 0.72 | HPGD (0.58) | GPR119KDM4EPKM | |
| SCHEMBL28824366 | 0.72 | ESR2 (0.48) | GPR119KDM4E | |
| SCHEMBL976218 | 0.71 | ESR2 (0.58) | PRMT5WDR77KDM4E | |
| SCHEMBL11889711 | 0.71 | HPGD (0.47) | GPR119KDM4EPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0698023-B1 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO INC (US) | 2000-08-23 | — | — | EP | disclosed |
| EP-0698023-A4 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO INC (US) | 1997-07-02 | — | — | EP | disclosed |
| EP-0698023-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO. INC. (US) | 1996-02-28 | — | — | EP | disclosed |
| WO-1994026745-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1994-11-24 | — | — | WO | disclosed |
| US-5334596-A | Anticoagulants | MERCK & CO., INC. (US) | 1994-08-02 | — | — | US | disclosed |