Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5764293 | 0.88 | DRD2 (0.53) | NPC1RAB9AL3MBTL1 | |
| SCHEMBL24582713 | 0.85 | NPC1 (0.54) | NPC1RAB9AL3MBTL1 | |
| SCHEMBL1000224 | 0.85 | NPC1 (0.54) | NPC1RAB9AL3MBTL1 | |
| SCHEMBL3208272 | 0.85 | NPC1 (0.54) | NPC1RAB9AL3MBTL1 | |
| SCHEMBL7036798 | 0.82 | PTPN1 (0.52) | NPC1RAB9AL3MBTL1 | |
| SCHEMBL12474768 | 0.82 | NPC1 (0.51) | NPC1RAB9AL3MBTL1 | |
| SCHEMBL9252347 | 0.81 | NPSR1 (0.58) | — | |
| SCHEMBL7038704 | 0.81 | LMNA (0.53) | — | |
| SCHEMBL10646917 | 0.80 | NPC1 (0.48) | NPC1RAB9AL3MBTL1 | |
| SCHEMBL27575924 | 0.80 | NOTUM (0.58) | NPC1RAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0244836-B1 | TRIPEPTIDE DERIVATIVES | Dainippon Pharmaceutical Co., Ltd. (JP) | 1993-08-18 | — | — | EP | disclosed |
| US-4826814-A | INHIBITORS OF ANGIOTENSIN CONVERTING ENZYME | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1989-05-02 | — | — | US | disclosed |
| EP-0244836-A2 | Tripeptide derivatives | Dainippon Pharmaceutical Co., Ltd. (JP) | 1987-11-11 | — | — | EP | disclosed |