Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRHR | P34981 | 6/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7318759 | 0.94 | TRHR (0.54) | TRHR | |
| Montirelin SCHEMBL4955895 | 0.89 | TRHR (0.55) | TRHR | |
| Montirelin SCHEMBL29405744 | 0.89 | TRHR (0.55) | TRHR | |
| Montirelin SCHEMBL7311976 | 0.89 | TRHR (0.55) | TRHR | |
| Montirelin SCHEMBL3098148 | 0.89 | TRHR (0.55) | TRHR | |
| Montirelin SCHEMBL7354006 | 0.89 | TRHR (0.55) | TRHR | |
| SCHEMBL9818117 | 0.89 | TRHR (0.52) | TRHR | |
| Montirelin SCHEMBL3095581 | 0.88 | TRHR (0.54) | TRHR | |
| Montirelin SCHEMBL8498903 | 0.86 | TRHR (0.52) | TRHR | |
| SCHEMBL7773056 | 0.84 | TRHR (0.56) | TRHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4877784-A | ANTIEPILEPTIC AGENTS | NIPPON SHINYAKU CO., LTD. (JP) | 1989-10-31 | — | — | US | claimed |
| EP-0382842-B1 | NOOTROPIC | Grünenthal GmbH (DE) | 1993-09-22 | — | — | EP | disclosed |
| US-4956364-A | 6-ALKYL-5-OXO-3-THIOMORPHOLINYLCARBONYLHISTIDYLPROLINAMIDE | NIPPON SHINYAKU CO., LTD. (JP) | 1990-09-11 | — | — | US | disclosed |
| EP-0382842-A1 | NOOTROPIC | Grünenthal GmbH (DE) | 1990-08-22 | — | — | EP | disclosed |
| US-4877784-A | ANTIEPILEPTIC AGENTS | NIPPON SHINYAKU CO., LTD. (JP) | 1989-10-31 | — | — | US | disclosed |