SCHEMBL9818117

SCHEMBL9818117

C=CCC1SCC(C(=O)N[C@@H](Cc2c[nH]cn2)C(=O)N2CCC[C@H]2C(N)=O)NC1=O

nearest known ligand 0.52

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ TRHR P34981 6/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7318759 0.90 TRHR (0.54) TRHR
SCHEMBL7310894 0.89 TRHR (0.52) TRHR
Montirelin SCHEMBL29405744 0.87 TRHR (0.55) TRHR
Montirelin SCHEMBL3098148 0.87 TRHR (0.55) TRHR
Montirelin SCHEMBL4955895 0.87 TRHR (0.55) TRHR
Montirelin SCHEMBL7311976 0.87 TRHR (0.55) TRHR
Montirelin SCHEMBL7354006 0.87 TRHR (0.55) TRHR
Montirelin SCHEMBL3095581 0.86 TRHR (0.54) TRHR
Montirelin SCHEMBL8498903 0.84 TRHR (0.52) TRHR
SCHEMBL7773056 0.83 TRHR (0.56) TRHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0317624-B1 THYROTROPIN-RELEASING HORMONE ANALOGS IN CNS INJURY MEDICIS CORPORATION (US) 1991-12-11 — — EP disclosed
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