Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 4/20 | 0.48 |
| ▸ | NISCH | Q9Y2I1 | 2/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | ADK | P55263 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | F2RL1 | P55085 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.35 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.35 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.35 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | EYA3 | Q99504 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8352818 | 0.80 | MCL1 (0.40) | ADRA2ANISCHALDH1A1KMT2AKDM4E | |
| SCHEMBL28270082 | 0.75 | NISCH (0.50) | ADRA2ANISCHMTORADKALDH1A1 | |
| SCHEMBL11714060 | 0.74 | GAA (0.51) | ADRA2ANISCHMTORADKALDH1A1 | |
| SCHEMBL3702761 | 0.72 | ADRA2A (0.48) | ADRA2ANISCHMTORADKALDH1A1 | |
| SCHEMBL11717071 | 0.71 | KDM4E (0.42) | ADRA2ANISCHMTORADKALDH1A1 | |
| SCHEMBL3053174 | 0.70 | ADRA2A (0.46) | ADRA2ANISCHMTORADKALDH1A1 | |
| SCHEMBL27945010 | 0.70 | NISCH (0.50) | ADRA2ANISCHMTORADKALDH1A1 | |
| SCHEMBL8787263 | 0.70 | ADRA2A (0.64) | ADRA2ANISCHMTORADKALDH1A1 | |
| SCHEMBL26259955 | 0.69 | NISCH (0.61) | ADRA2ANISCHMTORADKALDH1A1 | |
| SCHEMBL6001368 | 0.69 | NISCH (0.52) | ADRA2ANISCHMTORADKALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0514193-A1 | N-linked imidazolyl-methyl benzofuran derivatives with antihypotensive activity | GLAXO GROUP LIMITED (GB) | 1992-11-19 | — | — | EP | disclosed |