Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 2/20 | 0.40 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.40 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.40 |
| ▸ | CDC7 | O00311 | 1/20 | 0.40 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.40 |
| ▸ | IGF1R | P08069 | 1/20 | 0.40 |
| ▸ | CLK2 | P49760 | 1/20 | 0.40 |
| ▸ | GSK3A | P49840 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7310923 | 0.80 | ADRA2A (0.48) | ALDH1A1KMT2AADRA2AADRA2BADRA2C | |
| SCHEMBL8351963 | 0.72 | ROCK1 (0.45) | PIM1PIM2ALDH1A1NISCHNPC1 | |
| SCHEMBL6824166 | 0.72 | LMNA (0.45) | ALDH1A1LMNAADRA2AADRA2BADRA2C | |
| SCHEMBL16418296 | 0.70 | ADRA2A (0.69) | ALDH1A1LMNAKMT2AADRA2AADRA2B | |
| SCHEMBL14409919 | 0.68 | MCL1 (0.59) | MCL1DYRK1AALDH1A1LMNAKMT2A | |
| SCHEMBL15750031 | 0.68 | AHR (0.52) | MCL1ALDH1A1LMNAKMT2AGPR55 | |
| SCHEMBL8524127 | 0.67 | NISCH (0.47) | ALDH1A1LMNAADRA2AADRA2BADRA2C | |
| SCHEMBL8349193 | 0.67 | ROCK1 (0.48) | PIM1PIM2KMT2ANISCHNPC1 | |
| SCHEMBL3631532 | 0.65 | RAB9A (0.50) | GSK3AGSK3BALDH1A1KMT2AAHR | |
| SCHEMBL28196748 | 0.65 | AHR (0.48) | MCL1ALDH1A1LMNAKMT2AGPR55 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999032112-A1 | METHOD FOR TREATING DIABETES | ELI LILLY AND COMPANY (US) | 1999-07-01 | — | — | WO | disclosed |