Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 3/20 | 0.64 |
| ▸ | MAOB | P27338 | 5/20 | 0.52 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.49 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | ADK | P55263 | 1/20 | 0.41 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.38 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 3/20 | 0.38 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.36 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.36 |
| ▸ | GABRP | O00591 | 1/20 | 0.36 |
| ▸ | GABRD | O14764 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL563350 | 0.78 | ADRA2A (1.00) | ADRA2AMAOBADRA2BADRA2CMEN1 | |
| Hydrochloric Acid SCHEMBL30865655 | 0.77 | ADRA2A (0.97) | ADRA2AMAOBADRA2BADRA2CMEN1 | |
| Hydrochloric Acid SCHEMBL9295322 | 0.77 | ADRA2A (0.97) | ADRA2AMAOBADRA2BADRA2CMEN1 | |
| SCHEMBL8787416 | 0.74 | ALDH1A1 (0.49) | MAOBMEN1ALDH1A1KMT2ANPC1 | |
| SCHEMBL26661230 | 0.74 | MAOB (0.75) | MAOBCYP1B1CYP1A1CYP1A2PLA2G2A | |
| SCHEMBL8787065 | 0.74 | MAOB (0.53) | MAOBMEN1ALDH1A1KMT2ACYP1B1 | |
| SCHEMBL8787194 | 0.72 | MAOB (0.50) | MAOBCYP1B1CYP1A1CYP1A2GRM4 | |
| SCHEMBL8787940 | 0.71 | MAOB (0.49) | MAOBCYP1B1CYP1A1CYP1A2GRM4 | |
| SCHEMBL3702761 | 0.70 | ADRA2A (0.48) | ADRA2AADRA2BADRA2CMEN1ALDH1A1 | |
| SCHEMBL7310923 | 0.70 | ADRA2A (0.48) | ADRA2AADRA2BADRA2CMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5698575-A | Chromone compounds, pharmaceutical compositions containing the same, and use of the same | KUREHA CHEMICAL INDUSTRY CO., LTD. (JP) | 1997-12-16 | — | — | US | disclosed |
| EP-0758649-A1 | Chromone derivative, process for preparing same and pharmaceutical composition | Kureha Chemical Industry Co., Ltd. (JP) | 1997-02-19 | — | — | EP | disclosed |