SCHEMBL731096

SCHEMBL731096

CC(N)c1ccccc1S(N)(=O)=O

nearest known ligand 0.48

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CA2 P00918 11/20 0.48
CA1 P00915 9/20 0.48
CA9 Q16790 9/20 0.48
CA12 O43570 5/20 0.48
CA6 P23280 3/20 0.48
CA5A P35218 3/20 0.48
CA4 P22748 2/20 0.48
CA7 P43166 2/20 0.48
CA5B Q9Y2D0 2/20 0.48
CYP2C9 P11712 1/20 0.48
CA14 Q9ULX7 1/20 0.48
PTGES2 Q9H7Z7 3/20 0.44
ACHE P22303 1/20 0.40
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2D6 P10635 1/20 0.39
NFKB1 P19838 1/20 0.39
PNMT P11086 1/20 0.39
LDHA P00338 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1106519 0.85 CA1 (0.53) CA2CA1CA9CA12CA6
SCHEMBL30593603 0.85 CA1 (0.53) CA2CA1CA9CA12CA6
SCHEMBL6680955 0.85 GAA (0.46) CA2CA1CA9CA12ACHE
SCHEMBL5140208 0.83 L3MBTL1 (0.40) CA2CA1CA9CA12ACHE
SCHEMBL9493369 0.83 CA1 (0.51) CA2CA1CA9CA12CA6
Potassium SCHEMBL9493381 0.83 CA1 (0.51) CA2CA1CA9CA12CA6
Hydrochloric Acid SCHEMBL28262186 0.83 CA1 (0.51) CA2CA1CA9CA12CA6
SCHEMBL3284628 0.82 HTR2A (0.48) CA2CA1CA9CA12CA6
SCHEMBL14008998 0.82 CYP1A2 (0.38) CA2CA1CA9CA12ACHE
SCHEMBL2517262 0.82 MYC (0.42) CYP1A2CYP3A4CYP2D6NFKB1PNMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114235990-B Tuberculosis serum marker screening method and application 宁夏医科大学 2024-11-26 CN claimed
CN-114235990-A Tuberculosis serum marker screening method and application 宁夏医科大学 2022-03-25 CN claimed
EP-0783366-B1 CHROMATOGRAPHIC RESINS AND METHODS FOR USING SAME UNIV MASSEY (NZ) 2004-08-18 EP claimed
US-5652348-A SOLID SUPPORT MATRIX, IONIZABLE LIGANDS SELECTED RELATIVE TO TARGET COMPOUND MASSEY UNIVERSITY (NZ) 1997-07-29 US claimed
EP-0783366-A1 CHROMATOGRAPHIC RESINS AND METHODS FOR USING SAME MASSEY UNIVERSITY (NZ) 1997-07-16 EP claimed
WO-1996009116-A1 CHROMATOGRAPHIC RESINS AND METHODS FOR USING SAME MASSEY UNIVERSITY (NZ) 1996-03-28 WO claimed
CN-114235990-B Tuberculosis serum marker screening method and application 宁夏医科大学 2024-11-26 CN disclosed
CN-117732437-A Preparation and drug target identification application of switchable sulfhydryl functional magnetic silica nanoparticle 北京青莲百奥生物科技有限公司 2024-03-22 CN disclosed
CN-117732437-A Preparation and drug target identification application of switchable sulfhydryl functional magnetic silica nanoparticle 北京青莲百奥生物科技有限公司 2024-03-22 CN disclosed
CN-114235990-A Tuberculosis serum marker screening method and application 宁夏医科大学 2022-03-25 CN disclosed
US-8138209-B2 Substituted picolinamides as MAO-B inhibitors useful for treating obesity JENRIN DISCOVERY, INC. (US) 2012-03-20 US disclosed
WO-2009140743-A2 BLOOD IMAGING KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2009-11-26 WO disclosed
US-20080138291-A1 Sulfonamide Derivatives Having Carbonic Anhydrase Inhibiting Activity and their Use as Therapeutic and Diagnostic Agents UNION LIFE SCIENCES LTD. (GB) 2008-06-12 US disclosed
WO-2006137092-A1 FLUORESCENT SULFONAMIDE DERIVATIVES HAVING CARBONIC ANHYDRASE INHIBITING ACTIVITY AND THEIR USE AS THEAPEUTIC AND DIAGNOSTIC AGENTS SUPURAN CLAUDIU T (IT) 2006-12-28 WO disclosed
WO-2006137009-A2 FLUORESCENT SULFONAMIDE DERIVATIVES HAVING CARBONIC ANHYDRASE INHIBITING ACTIVITY AND THEIR USE AS THERAPEUTIC AND DIAGNOSTIC AGENTS UNION LIFE SCIENCES LTD (GB) 2006-12-28 WO disclosed
EP-0783366-B1 CHROMATOGRAPHIC RESINS AND METHODS FOR USING SAME UNIV MASSEY (NZ) 2004-08-18 EP disclosed
US-5945520-A RESIN OF SOLID SUPPORT MATRIX, SPACER ARM AND IONIZABLE FUNCTIONALITY; SPECIFICALLY DESIGNED TO BIND THE TARGET COMPOUND FROM AN AQUEOUS SOLUTION AT BOTH A LOW AND HIGH IONIC STRENGTH MASSEY UNIVERSITY (NZ) 1999-08-31 US disclosed
US-5652348-A SOLID SUPPORT MATRIX, IONIZABLE LIGANDS SELECTED RELATIVE TO TARGET COMPOUND MASSEY UNIVERSITY (NZ) 1997-07-29 US disclosed
EP-0783366-A1 CHROMATOGRAPHIC RESINS AND METHODS FOR USING SAME MASSEY UNIVERSITY (NZ) 1997-07-16 EP disclosed
WO-1996009116-A1 CHROMATOGRAPHIC RESINS AND METHODS FOR USING SAME MASSEY UNIVERSITY (NZ) 1996-03-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080138291-A1 Sulfonamide Derivatives Having Carbonic Anhydrase Inhibiting Activity and their Use as Therapeutic and Diagnostic Agents CA9, CA4, CA2 CA2 3/4885CA1 8/4885CA9 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.